A Co-morbid Condition of Warts and Vitiligo Treated with Individualized Homeopathy: An Evidence-Based Case Report

Akhyaya Kumar Prusty; Preeti Bhandari

doi:10.1055/s-0041-1733975

Homeopathy, Table of Contents

Homeopathy 2022; 111(02): 139-146
DOI: 10.1055/s-0041-1733975

Clinical Case Report

A Co-morbid Condition of Warts and Vitiligo Treated with Individualized Homeopathy: An Evidence-Based Case Report

Akhyaya Kumar Prusty

¹Regional Research Institute for Homoeopathy, Puri, Odisha, under Central Council for Research in Homoeopathy, Ministry of AYUSH, Govt. of India, New Delhi, India

,

Preeti Bhandari

¹Regional Research Institute for Homoeopathy, Puri, Odisha, under Central Council for Research in Homoeopathy, Ministry of AYUSH, Govt. of India, New Delhi, India

› Author Affiliations

Abstract

Background Whilst warts and vitiligo are both common skin diseases, their co-morbidity is rare. Here we present a clinical case of warts with vitiligo to illustrate the utility of individualized homeopathic treatment.

Method The homeopathic medicine Sepia officinalis was prescribed, based on individualization. During follow-up, changes were documented by photographs. The non-invasive methods ORIDL (Outcome Related to Impact on Daily Living), VASI (Vitiligo Area and Scoring Index), and VETF (Vitiligo European Task Force) were used to assess treatment progress. Possible causal attribution of outcome with treatment was evaluated using the Modified Naranjo Criteria for Homeopathy (MONARCH).

Result There was a marked improvement of vitiligo, along with the disappearance of warts, as evidenced photographically. VASI and VETF scores were significantly reduced. Main complaints, as well as overall well-being, improved on the ORIDL scale (+3). The MONARCH score (+9) suggested that the clinical improvement was attributable to the homeopathic intervention.

Conclusion The study suggests a significant role for individualized homeopathic treatment in the co-morbidity of warts and vitiligo.

Keywords

individualized homeopathy - co-morbidity - wart - vitiligo - Sepia officinalis

Full Text

References

References
1 Khanna N. Illustrated Synopsis of Dermatology and Sexually Transmitted Diseases. 6th ed.. Gurgaon, Haryana: Elsevier India Private Limited; 2019
2 Loo SK-F, Tang WY-M. Warts (non-genital). BMJ Clin Evid 2014; 2014: 1710
3 Whitton M, Pinart M, Batchelor JM. et al. Evidence-based management of vitiligo: summary of a Cochrane systematic review. Br J Dermatol 2016; 174: 962-969
4 Ezzedine K, Eleftheriadou V, Whitton M, van Geel N. Vitiligo. Lancet 2015; 386: 74-84
5 van Geel N, Mollet I, Brochez L. et al. New insights in segmental vitiligo: case report and review of theories. Br J Dermatol 2012; 166: 240-246
6 Wakkee M, Nijsten T. Comorbidities in dermatology. Dermatol Clin 2009; 27: 137-147
7 Mohan GC, Silverberg JI. Association of vitiligo and alopecia areata with atopic dermatitis: A systematic review and meta-analysis. JAMA Dermatol 2015; 151: 522-528
8 Pandey S, Pandit RK. Individualized Homoeopathic approach in a case of vitiligo with hypothyroidism—a case report. IJA-CARE 2020; 4: 125-134
9 Park JM, Kim HJ, Bae BG, Park YK. A case of concurrent vitiligo and psoriasis. Ann Dermatol 2009; 21: 330-333
10 Neelagiri S, Janardhan B, Reddy KSR, Sreedhar V. Co-occurrence of psoriasis, vitiligo, and lichen planus in a single patient. Indian J Paediatr Dermatol 2018; 19: 157-160
11 Petrosian R, Liesionyte K, Petkevicius A, Kucinskiene V, Makstiene J, Valiukeviciene S. Lichen planus verrucosus in an association with vitiligo. Aktuelle Derm 2015; 41: 425-427
12 Ito T, Yoshida Y, Adachi K, Furue M, Yamamoto O. Wart with depigmented halo and generalized vitiligo. Yonago Acta Med 2012; 55: 81-82
13 Wilmer EN, Burkhart CN, Morrell DS. Goodbye warts, hello vitiligo: Candida antigen-induced depigmentation. Pediatr Dermatol 2013; 30: e214-e215
14 Sterling JC, Gibbs S, Haque Hussain SS, Mohd Mustapa MF, Handfield-Jones SE. British Association of Dermatologists' guidelines for the management of cutaneous warts 2014. Br J Dermatol 2014; 171: 696-712
15 Sanchez MR. Duct tape for the treatment of common warts in adults. JAMA Dermatol 2013; 149: 959
16 Pazyar N, Yaghoobi R, Bagherani N, Kazerouni A. A review of applications of tea tree oil in dermatology. Int J Dermatol 2013; 52: 784-790
17 Fox PA, Tung MY. Human papillomavirus: burden of illness and treatment cost considerations. Am J Clin Dermatol 2005; 6: 365-381
18 Bhadoriya Y. Homeopathic management of psoriasis—a case study. World J Pharm Med Res 2020; 6: 250-252
19 Parveen S. Homoeopathic treatment in a case of co-morbid atopic dermatitis and depressive disorder. Indian J Res Homoeopath 2016; 10: 75-82
20 Denisova TG, Gerasimova LI, Pakhmutova NL, Mahesh S, Vithoulkas G. Individualized homeopathic therapy in a case of obesity, dysfunctional uterine bleeding, and autonomic dystonia. Am J Case Rep 2018; 19: 1474-1479
21 Reilly D, Mercer SW, Bikker AP, Harrison T. Outcome related to impact on daily living: preliminary validation of the ORIDL instrument. BMC Health Serv Res 2007; 7: 139
22 Hamzavi I, Jain H, McLean D, Shapiro J, Zeng H, Lui H. Parametric modeling of narrowband UV-B phototherapy for vitiligo using a novel quantitative tool: the Vitiligo Area Scoring Index. Arch Dermatol 2004; 140: 677-683
23 Komen L, da Graça V, Wolkerstorfer A, de Rie MA, Terwee CB, van der Veen JPW. Vitiligo Area Scoring Index and Vitiligo European Task Force assessment: reliable and responsive instruments to measure the degree of depigmentation in vitiligo. Br J Dermatol 2015; 172: 437-443
24 Taïeb A, Picardo M. VETF Members. The definition and assessment of vitiligo: a consensus report of the Vitiligo European Task Force. Pigment Cell Res 2007; 20: 27-35
25 Lamba CD, Gupta VK, van Haselen R. et al. Evaluation of the Modified Naranjo Criteria for assessing causal attribution of clinical outcome to homeopathic intervention as presented in case reports. Homeopathy 2020; 109: 191-197
26 Stub T, Salamonsen A, Alraek T. Is it possible to distinguish homeopathic aggravation from adverse effects? A qualitative study. Forsch Komplement Med 2012; 19: 13-19
27 Mahesh S, Mallappa M, Tsintzas D, Vithoulkas G. Homeopathic treatment of vitiligo: a report of fourteen cases. Am J Case Rep 2017; 18: 1276-1283
28 Ganguly S, Saha S, Koley M, Mondal R. Homeopathic treatment of vitiligo: an open observational pilot study. Int J High Dilution Res 2013; 12: 168-177
29 Shaikh M. Case studies for treatment of warts with Homoeopathy. Indian J Res Homoeopath 2016; 10: 272-278
30 Sahoo A, Barik B, Hati A, Paital B. Right potency matters: a case report of homoeopathic treatment of verruca palmaris. Homœopathic Links 2018; 31: 204-208
31 Oza P. Homeopathic management of warts. Indian J Drugs Dermatol 2016; 2: 45-47
32 Pingel S. Homeopathy. Basic aspects and principles of use in dermatology. Hautarzt 1992; 43: 475-482
33 Roberts HA. The Principles and Art of Cure by Homoeopathy. Delhi: B. Jain Publishers (P) Ltd; 2012
34 Hahnemann S. Organon of Medicine. Combined 5th and 6th ed. Dudgeon RE and Boericke W (Translators). Delhi: B. Jain Publishers (P) Ltd.; 2015
35 Labrecque M, Audet D, Latulippe LG, Drouin J. Homeopathic treatment of plantar warts. CMAJ 1992; 146: 1749-1753
36 Kainz JT, Kozel G, Haidvogl M, Smolle J. Homoeopathic versus placebo therapy of children with warts on the hands: a randomized, double-blind clinical trial. Dermatology 1996; 193: 318-320
37 Manchanda RK, Mehan N, Bahl R, Atey R. Double blind placebo controlled clinical trials of homoeopathic medicines in warts and molluscum contagiosum. CCRH Q Bull 1997; 19: 25-29
38 Ulbrich-Zürni S, Teut M, Roll S, Mathie RT. The N-of-1 clinical trial: a timely research opportunity in homeopathy. Homeopathy 2018; 107: 10-18